個(gè)人簡(jiǎn)介

孔德興，教授，博士生導(dǎo)師。畢業(yè)于復(fù)旦大學(xué)并獲理學(xué)博士、美國(guó)哈佛大學(xué)博士后。新鄉(xiāng)醫(yī)學(xué)院數(shù)理醫(yī)學(xué)院創(chuàng)始院長(zhǎng)，浙江大學(xué)求是特聘教授。兼任國(guó)家衛(wèi)生健康委能力建設(shè)和繼續(xù)教育中心-超聲大數(shù)據(jù)創(chuàng)新應(yīng)用中心主任、 國(guó)家藥監(jiān)局器審中心人工智能醫(yī)療器械創(chuàng)新合作平臺(tái)管委會(huì)副主任兼任數(shù)據(jù)治理工作組組長(zhǎng)、中國(guó)生物醫(yī)學(xué)工程學(xué)會(huì)醫(yī)學(xué)人工智能分會(huì)主任委員、中國(guó)工業(yè)與應(yīng)用數(shù)學(xué)學(xué)會(huì)數(shù)學(xué)與醫(yī)學(xué)交叉學(xué)科專(zhuān)委會(huì)主任委員、中國(guó)醫(yī)學(xué)裝備人工智能聯(lián)盟專(zhuān)家委員會(huì)委員、浙江省科協(xié)數(shù)字科技學(xué)會(huì)聯(lián)合體主席、浙江省數(shù)理醫(yī)學(xué)學(xué)會(huì)理事長(zhǎng)、中國(guó)人民解放軍總醫(yī)院（北京301醫(yī)院）客座教授、中國(guó)人民解放軍醫(yī)學(xué)院客座教授、中國(guó)人民解放軍國(guó)防科技大學(xué)客座教授、英國(guó)Northumbria University客座教授。國(guó)家自然科學(xué)基金重大項(xiàng)目首席科學(xué)家。截止目前，在國(guó)際著名學(xué)術(shù)期刊上發(fā)表學(xué)術(shù)論文160多篇；由科學(xué)出版社出版專(zhuān)著2部，由日本數(shù)學(xué)會(huì)出版英文專(zhuān)著1部，高等教育出版社出版研究生教材、本科生教材各1部；申請(qǐng)國(guó)家發(fā)明專(zhuān)利22項(xiàng)（目前授權(quán)7項(xiàng)、15項(xiàng)公告中）、軟件著作權(quán)6項(xiàng)。以第一完成人獲2022年中國(guó)產(chǎn)學(xué)研合作創(chuàng)新獎(jiǎng)、2022年中國(guó)工業(yè)與應(yīng)用數(shù)學(xué)學(xué)會(huì)“CSIAM應(yīng)用數(shù)學(xué)落地成果獎(jiǎng)”、2011年浙江省科學(xué)技術(shù)獎(jiǎng)二等獎(jiǎng)、2018年教育部科學(xué)技術(shù)進(jìn)步獎(jiǎng)二等獎(jiǎng)、2019年浙江省級(jí)自然科學(xué)獎(jiǎng)二等獎(jiǎng)。2005年入選教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃，2012年入選浙江省151人才計(jì)劃（第一層次），2018年入選浙江省首屆“萬(wàn)人計(jì)劃”科技創(chuàng)新領(lǐng)軍人才。2001年入選上海市青年科技啟明星計(jì)劃、2005年入選教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃、2012年入選浙江省151人才工程第一層次培養(yǎng)人員計(jì)劃、2018年入選首屆浙江省萬(wàn)人計(jì)劃科技創(chuàng)新領(lǐng)軍人才。

承擔(dān)項(xiàng)目

1. 國(guó)家自然科學(xué)基金重大研究計(jì)劃集成項(xiàng)目，91630311、醫(yī)學(xué)影像配準(zhǔn)與融合的建模和算法、2017/01-2019/12、主持

2. 國(guó)家自然科學(xué)基金重大研究計(jì)劃培育項(xiàng)目，91330105、非光滑凸優(yōu)化問(wèn)題的快速算法及其在圖像分析中的應(yīng)用、2014/01-2016/12、主持

3. 浙江省科技廳重大科技專(zhuān)項(xiàng)，2014C03016、精確肝癌射頻消融系統(tǒng)：腫瘤精確定位及手術(shù)方案輔助設(shè)計(jì)、2014/07-2017/06、主持

4. 國(guó)家自然科學(xué)基金數(shù)學(xué)天元專(zhuān)項(xiàng)基金項(xiàng)目，11326033、醫(yī)學(xué)影像學(xué)中問(wèn)題驅(qū)動(dòng)的若干應(yīng)用數(shù)學(xué)問(wèn)題、2013/07-2014/06、主持

5. 國(guó)家自然科學(xué)基金面上項(xiàng)目，11271323、雙曲平均曲率流、2013/01-2016/12、主持

6. 浙江省自然科學(xué)基金委重點(diǎn)項(xiàng)目，LZ13A010002、Minkowski 時(shí)空中的類(lèi)時(shí)極值子流形、2013/01-2016/12、主持

7. 國(guó)家自然科學(xué)基金面上項(xiàng)目，10971190、雙曲幾何流、2010/01-2012/12、主持

8. 國(guó)家自然科學(xué)基金面上項(xiàng)目，10671124、相對(duì)論弦與膜的非線性動(dòng)力學(xué)、2007/01-2009/12、主持

9. 教育部新世紀(jì)優(yōu)秀人才，數(shù)學(xué)物理、2005年、主持

10.國(guó)家自然科學(xué)基金面上項(xiàng)目，10371073、超彈性材料中的非線性波、2004/01-2006/12、主持

11.國(guó)家自然科學(xué)基金面上項(xiàng)目，10001024、非線性雙曲波中奇性的形成傳播、2001/01-2003/12、主持

部分代表性論文：

1. Qianting Ma and De-Xing Kong*, A new variational model for joint restoration and segmentation based on the Mumford-Shah model, Journal of Visual Communication and Image Representation, 2018.

2. Rendong Chen, Tian-An Jiang, Kaifeng Wang, Fang Lu, Dexing Kong*, Automatic Radiofrequency Ablation Planning Based on Constrained Clustering Process for Hepatic Tumors, IEEE Transactions on Biomedical Engineering 65 (2018), 645-657

3. Zixu Yan, Feng Chen, Dexing Kong*, Liver Venous Tree Separation via Twin-line RANSAC and Murray’s Law, accepted by IEEE Trans. Medical Imaging, 2017.

4. Jinlian Ma, Fa Wu, Tian-An Jiang, Qiyu Zhao, Dexing Kong*, Ultrasound image based thyroid nodule automatic segmentation using convolutional neural networks International Journal of Computer Assisted Radiology and Surgery, International Journal of Computer Assisted Radiology and Surgery, 2017. (DOI 10.1007/s11548-017-1649-7)

5. Qianting Ma, Fangfang Dong, Dexing Kong*, A fractional differential fidelity-based PDE model for image denoising, Machine Vision and Applications 28 (2017), 635-647. (doi:10.1007/s00138-017-0857-z, August 2017, Volume 28, Issue 5C6, pp 635-647)

6. Dexing Kong, Changhua Wei, Lifespan of smooth solutions for timelike extremal surface equation in de Sitter spacetime, accepted by J. Math. Phys., 2017.

7. Jinlian Ma, Fa Wu, Tian-An Jiang, Jiang Zhu, Dexing Kong*, Cascade convolutional neural networks for automatic detection of thyroid nodules in ultrasound images, Med. Phys. 44 (5), 1978-1691, May 2017.

8. Zixu Yan, Feng Chen, Fa Wu, Dexing Kong*, Inferior Vena Cava Segmentation With Parameter Propagation And Graph Cut, International Journal of Computer Assisted Radiology and Surgery (2017), DOI 10.1007/s11548-017-1582-9.

9. Jinlian Ma, Fa Wu, Jiang Zhu, Dong Xu, Dexing Kong*, A Pre-trained Convolutional Neural Network Based Method for Thyroid Nodule Diagnosis, Ultrasonics (2016), Ultrasonics 73 (2017), 221-230.

10.Peijun Hu, Fa Wu, Jialin Peng, Ping Liang, Dexing Kong*, Automatic 3D liver segmentation based on deep learning and globally optimized surface evolution, Phys. Med. Biol. 61 (2016), 8676-8698.

11.Peijun Hu, Fa Wu, Jialin Peng, Yuanyuan Bao, Feng Chen, Dexing Kong*, Automatic abdominal multi-organ segmentation using deep convolutional neural network and time-implicit level sets, Int J CARS (2016), DOI 10.1007/s11548-016-1501-5.

12.Fang Lu, Fa Wu, Peijun Hu, Zhiyi Peng, Dexing Kong*, Automatic 3D liver location and segmentation via convolutional neural network and graph cut, Int J CARS (2016), doi:10.1007/s11548-016-1467-3.

13.Jialin Peng, Peijun Hu, Fang Lu, Zhiyi Peng, Dexing Kong and Hongbo Zhang, 3D liver segmentation using multiple region appearances and graph cuts, Medical Physics 42, 6840 (2015).

14.Jialin Peng, Y. C. Hon and De-Xing Kong*, A Structural low rank regularization method for single image super-resolution, Machine Vision and Applications 26 (2015), 991-1005.

15.Zheng Xie, Jiang Zhu, De-Xing Kong* and Jianping Li, A random geometric graph built on a time-varying Riemannian manifold, Physica A 436 (2015), 492-498.

16.De-Xing Kong and Chen Zhao, Light-likeness of boundaries of extremal surfaces of mixed type in physical spaceCtimes, J. Math. Anal. Appl. 422 (2015), 1026-1033.

17.Qiong Lou, Jialin Peng and De-Xing Kong*, A variational formulation for physical noised image segmentation, Appl. Math. J. Chinese Univ. 30 (2015), 77-92.

18.Shou-Jun Huang, Hui-Hui Dai and De-Xing Kong, Global structure stability for the wave catching-up phenomena in a prestressed two-material bar, SIAM J. Appl. Math. 75 (2015), 585-604.

19.De-Xing Kong and Changhua Wei, Formation of singularities in one-dimensional Chaplygin gas, Journal of Hyperbolic Differential Equations 3, (2014), 521C561

20.Jialin Peng, Ye Wang and De-Xing Kong , Liver segmentation with constrained convex variational model, Pattern Recognition Letters 43 (2014), 81-88.

21.De-Xing Kong and Jinhua Wang, Einstein’s hyperbolic geometric flow, Journal of Hyperbolic Differential Equations 11 (2014), 249-267.

22.De-Xing Kong and Changhua Wei, The global existence and the life span of smooth solutions to a class of complex conservation laws, Nonlinear Analysis 95 (2014), 553-567.

23.De-Xing Kong and Changhua Wei, Formation and propagation of singularities in one-dimensional Chaplygin gas, Journal of Geometry and Physics 80 (2014), 58-70.

24.Jialin Peng, Fangfang Dong, Yunmei Chen and Dexing Kong*, A region-appearance-based adaptive variational model for 3D liver segmentation, Medical Physics 41,043502 (2014)

25.Zheng Xie, Enming Dong, Jianping Li, De-Xing Kong* and Ning Wu, Potential links by neighbor communities, Physica A 406 (2014), 244-252.

26.De-Xing Kong and Changhua Wei, Blowup of smooth solutions of a class of complex conservation laws, Journal of Mathematical Analysis and Applications 406 (2013), 464-474.

27.Kai-Feng Wang, Wei Pan, Fei Wang, Gao-Feng Wang, Pai Madhava, Hong- Ming Pan, De-Xing Kong* and Xiang-Guan Liu, Geometric Optimization of a Mathemat-ical Model of Radiofrequency Ablation in Hepatic Carcinoma, Asian Pacific Journal of Cancer Prevention 14 (2013), 6151-6158.

28.De-Xing Kong and Fa Wu, A New Type of Distributed Parameter Control Systems: Two-Point Boundary Value Problems for Infinite-Dimensional Dynamical Systems, Journal of Applied Mathematics, Article ID 454857 (http://dx.doi.org/10.1155/2013/454857), 2013.

29.De-Xing Kong and Xiao-Yan Li, Motion of Relativistic Strings on the Equatorial Plane in the Schwarzschild Space-Time, COMMUNICATIONS IN THEORETICAL PHYSICS 59 (2013), 80-86.

30.Shou-Jun Huang, Hui-Hui Dai, Zhen Chen and De-Xing Kong, Mathematical theory and analytical solutions for the wave catching-up phenomena in a nonlinearly elastic composite bar, PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES 468 (2012), 3882-3901.

31.Dan Long, Jinwei Wang, De-Xing Kong* and Minming Zhang, Automatic classification of early Parkinson’s disease with multi-modal MR imaging, PLOS ONE 7(11) (2012), e47714.

32.De-Xing Kong and Yu-Zhu Wang, Long-time behaviour of smooth solutions to the compressible Euler equations with damping in several space variables, IMA Journal of Applied Mathematics 77 (2012), 473-494.

33.Jialin Peng, Jinwei Wang and De-Xing Kong*, A new convex variational model for liver segmentation, ICPR 2012 (IAPR Best Scientific Paper Award).

34.Jialin Peng, Fangfang Dong and De-Xing Kong*, Recent advances of variational model in medical imaging and applications to computer aided surgery, Appl. Math. J. Chinese Univ. 27 (2012), 379-411

35.Z. Dong, Y. Chen, De-Xing Kong and Z. Wang, Symmetry reduction and exact solutions of a hyperbolic Monge-Amp`ere equation, Chinese Annals of Mathematics Series 33B (2012), 309-316.

36.De-Xing Kong, Kefeng Liu and Yu-Zhu Wang, Life-span of classical solutions to hyperbolic geometric flow in two space variables with slow decay initial data, Communications in Partial Differential Equations 36 (2011), 162-184.

37.De-Xing Kong, Kefeng Liu and Ming Shen, Time-Periodic Solutions of the Einstein’s Field Equations III: Physical Singularities, Science in China 54 (2011), 23-33.

38.De-Xing Kong and Qing-You Sun, Two-point boundary value problems and exact controllability for several kinds of linear and nonlinear wave equations, Journal of Physics: Conference Series 290 (2011), 012008.

39.De-Xing Kong, Kefeng Liu and Yu-Zhu Wang, Global existence of smooth solution-s to two-dimensional compressible isentropic Euler equations for Chaplygin gases, Science in China (Special Issue Dedicated to Professor Yang Lo on the Occasion of his 70th Birthday) 53 (2010), 719-738.

40.Wen-Rong Dai, De-Xing Kong and Kefeng Liu, Hyperbolic geometric flow (I): short-time existence and nonlinear stability, Pure and Applied Mathematics Quarterly (Special Issue: In honor of Michael Atiyah and Isadore Singer) 6 (2010), 331-359.

41.De-Xing Kong and Kefeng Liu, Time-Periodic Solutions of the Einstein’s Field Equations I: General Framework, Science in China, 53 (2010), 1213-1230.

42.De-Xing Kong, Kefeng Liu and Ming Shen, Time-Periodic Solutions of the Einstein’s Field Equations II: Geometric Singularities, Science in China, 53 (2010), 1507-1520.

43.Chun-Lei He and De-Xing Kong*, Spherical symmetric solutions for the motion of relativistic membranes in the Schwarzschild spacetime, Journal of Mathematical Physics 50 (2009), 083516.

44.De-Xing Kong and Qiang Zhang, Solution formula and time-periodicity for the motion of relativistic strings in the Minkowski space R¹⁺ⁿ, Physica D 238 (2009), 902-922.

45.De-Xing Kong and Zeng-Gui Wang, Formation of singularities in the motion of plane curves under hyperbolic mean curvature flow, Journal of Differential Equations 247 (2009), 1694-1719.

46.De-Xing Kong, Kefeng Liu and De-Liang Xu, The hyperbolic geometric flow on Riemann surfaces, Communications in Partial Differential Equations 34 (2009), 553-580.

47.Chun-Lei He, De-Xing Kong and Kefeng Liu, Hyperbolic mean curvature flow, Journal of Differential Equations 246 (2009), 373-390.

48.De-Xing Kong, Kefeng Liu and Zeng-Gui Wang, Hyperbolic mean curvature flow: Evolution of plane curves, Acta Mathematica Scientia (A special issue dedicated to Professor Wu Wenjun’s 90th birthday) 29 (2009), 493-514.

49.Wen-Rong Dai, De-Xing Kong and Kefeng Liu, Dissipative hyperbolic geometric flow, Asian Journal of Mathematics 12 (2008), 345-364.

50.De-Xing Kong, Extremal Sub-manifolds in Minkowski Space-time, in “Trends in Partial Differential Equations” ALM 10, Higher Education Press and International Press, Beijing-Boston, 2010, 213-240.

51.Chun-Lei He, Sen Hu, De-Xing Kong and Kefeng Liu, Generalized Ricci flow I: local existence and uniqueness, in Topology and Physics: Proceedings of the Nankai International Conference in Memory of Xiao-Song Lin (Tianjin, China, 2007), World Scientific Publishing Company, 2008, 142-159.

52.De-Xing Kong, Qiang Zhang and Qing Zhou, The dynamics of relativistic strings moving in the Minkowski space R¹⁺ⁿ, Communications in Mathematical Physics 269 (2007), 153-174.

53.De-Xing Kong and Kefeng Liu, Wave character of metrics and hyperbolic geometric flow, J. Math. Phys. 48(10), 103508 (2007), 1-14.

54.Wen-Rong Dai and De-Xing Kong , Global existence and asymptotic behavior of classical solutions of quasilinear hyperbolic systems with linearly degenerate characteristic fields, Journal of Differential Equations, 235 (2007), 127-165.

55.Shou-Jun Huang and De-Xing Kong*, Equations for the motion of relativistic torus in the Minkowski space R¹⁺ⁿ , J. Math. Phys. 48(8), 083510 (2007), 1-15.

56.De-Xing Kong, Hyperbolic geometric flow, in the Proceedings of ICCM (Hangzhou, China, 2007), Vol. II, Higher Education Press, Beijing, 2007, 95-110.

57.De-Xing Kong, Qing-You Sun and Yi Zhou, The equation for time-like extremal surfaces in Minkowski space R^1+(1+n), Journal of Mathematical Physics 47(1), 013503 (2006), 1-16.

58.Hui-Hui Dai and De-Xing Kong*, The propagation of impact-induced tensile waves in a kind of phase-transforming materials, Journal of Computational and Applied Mathematics 190 (2006), 57-73.

59.Hui-Hui Dai and De-Xing Kong*, Global Structure Stability of Impact-Induced Tensile Waves in a Rubber-like Material, IMA J. Appl. Math. 71 (2006), 14-33.

60.De-Xing Kong, Global structure instability of Riemann solutions of quasilinear hyperbolic systems of conservation laws: rarefaction waves, Journal of Differential Equations 219 (2005), 421-450.

61.De-Xing Kong and Hui Yao, Global exact boundary controllability of a class of quasilinear hyperbolic systems of conservation laws II, SIAM Journal on Control and Optimization 44 (2005), 140-158.

62.Wen-Rong Dai and De-Xing Kong*, Analysis of Singularities and Development of Shocks for a class of multidimensional hyperbolic systems of conservation laws, Math. Meth. Appl. Sci., 28 (2005), 1585-1611.

63.Hui-Hui Dai and De-Xing Kong*, Blowup of solutions to generalized Riemann problem for quasilinear hyperbolic systems of conservation laws, IMA J. Appl. Math. 69 (2004), 131-158.

64.De-Xing Kong and Tong Yang, Asymptotic behavior of global classical solutions of quasilinear hyperbolic systems, Communications in Partial Differential Equations 28 (2003), 1203-1220.

65.De-Xing Kong, Global structure stability of Riemann solutions of quasilinear hyperbolic systems of conservation laws: shocks and contact discontinuities, Journal of Differential Equations 188 (2003), 242-271.

66.De-Xing Kong and Tong Yang, A note on “Well-posedness for hyperbolic conservation laws”, Applied Mathematics Letters 16 (2003), 143-146.

67.De-Xing Kong, Global exact boundary controllability of a class of quasilinear hyper-bolic systems of conservation laws, Systems & Control Letters 47 (2002), 287-298.

68.De-Xing Kong, Formation and propagation of singularities for 2x2 quasilinear hyperbolic systems, Transactions of the American Mathematical Society 354 (2002), 3155-3179.

已授權(quán)發(fā)明專(zhuān)利：

1. 孔德興.基于快速凸優(yōu)化算法配準(zhǔn)三維CT與超聲肝臟圖像的方法.發(fā)明專(zhuān)利,.2018:5/29

2. 孔德興.一種利用橢球覆蓋腫瘤精確模擬射頻消融技術(shù)的方法.發(fā)明專(zhuān)利,.2018:4/6

3. 孔德興.基于卷積神經(jīng)網(wǎng)絡(luò)的全自動(dòng)的三維肝臟分割方法.發(fā)明專(zhuān)利,.2017:12/22

4. 孔德興.一種腫瘤射頻消融技術(shù)中精確定位三球覆蓋腫瘤的方法.發(fā)明專(zhuān)利,.2016:1/27

5. 孔德興.一種CAT圖像中肝臟與血管同時(shí)分割的方法.發(fā)明專(zhuān)利,.2016:1/4

6. 孔德興.CTA圖像中肝臟血管增強(qiáng)及肝臟與血管同時(shí)分割的方法.發(fā)明專(zhuān)利,.2014:1/4

7. 孔德興.雙曲方程圖像加密方法.發(fā)明專(zhuān)利,.2014:1/2